Product Introduction:
Albendazole Bolus is provided by Shanghai Sunke Industrial&Commercial Co.,ltd,a major Veterinary Medicine supplier in Health & Beauty wholesale industry in China.You can check out the specification of Albendazole Bolus below or get any optional result clicking into the following keywords Veterinary Medicine , Albendazole Bolus , 2500mg , Description , Features , Details and you can check the authentications and testimonials of Albendazole Bolus .
Description:
Albendazole
Albendazole is an "antihelmintic," or anti-worm, medication. It prevents worms from growing or multiplying in your body. Albendazole is used to treat infections caused by worms such as pork tapeworm and dog tapeworm. Albendazole interferes with various energy-producing processes of helminths (worms), including impairing the uptake of glucose (sugar) for energy. Albendazole is a medication which is used as an adjunct in the treatment of hydatid disease. Hydatid disease is caused by the parasite Echinococcus granulosus or Echinococcus multilocularis and presents as fluid-filled sacs (cysts) that grow in the liver, lungs and brain of infected individuals.
Albendazole is an orally administered broad-spectrum anthelmintic. Chemically it is Methyl 5-(propylthio)-2-benzimidazolecarbamate. Its molecular formula is C 12 H 15 N 3 O 2 S. Its molecular weight is 265.34. Albendazole is a white tco off-white powder. It is soluble in dimethylsulfoxide, strong acids and strong bases. It is slightly soluble in methanol, chloroform, ethyl acetate and acetonitrile. Albendazole is practically insoluble in water. Each white to off-white, film-coated tablet contains 200 mg of albendazole.
Albendazole works by interfering with proteins in either the worms intestine or absorptive cells. This leads to the worm not being able to absorb sugars which are essential for the its survival. Therefore the energy stores of the worm are depleted, and this leads to its eventual death within several days.
Action/Kinetics: Acts by inhibiting tubular polymerization, resulting in the loss of cytoplasmic microtubules and inability of the cell to function. Poorly absorbed from the GI tract; enhance absorption by ingesting a meal containing at least 40 g of fat. Rapidly converted to albendazole sulfoxide, the active metabolite. Peak plasma levels, sulfoxide: 2-5 hr. t1/2, terminal, of sulfoxide: 8-12 hr. Further metabolized to other metabolites with excretion through the bile, accounting for a portion of elimination.
